I was diagnosed with depression about 11 years ago went on meds for about 8 years and was off for about 3 years. Recently started on Pristiq about 7 months ago-generally have had good results. However, I now have increased blood pressure (borderline high - not too worried about it) and am really having a hard time taking off the my weight, which usually falls off once I start exercising. More concerning is I have now developed some female problems which I have never had before-I wonder if it might be linked to Pristiq. I have developed a uterine fibroid, an ovarian cyst and recently had to have an ablation due to severe hemorrhaging. The only difference in my life is the Pristiq and since it is a NEW drug - I JUST WONDER...