I've been on Fentanyl patches (50 mcg) for many years for lower back pain after 3 unsuccessful spine surgeries. About 2 years ago I felt the patch was not controlling the pain as well. Rather than raising the dose, I asked my doc if I could change the patch every 48 rather than 72 hours and he said "yes". That seemed to do a better job of pain control. Now I'm seeing a new doc who told me it's just a placebo effect and the amount of medicine absorbing into my skin is the same so changing the patch every 48 hours does not provide any different effect than changing it every 72 hours. Should I go back to the recommended dose, 72 hours, and will I have withdrawal symptoms if I do? I do occasionally have restlessness and anxiety symptoms - but that's the case with either dose. I really don't want to take more meds than I have to.