Can I have the explanation and the reference website or book names?
Hello pipazzo & welcome to the site. It's important because some medications can cause renal & liver problems. If you already have renal or liver problems you certainly wouldn't want to take a medication that would make it worse. Each medication has it's own set of warnings etc... & act differently so it would be hard to give you a reference to each one. If you have specific meds you are wanting to find out about, you can look them on at the top of the page under 'Drugs A toZ'. To give you a for instance, I have renal failure, & cannot take topomax. It was suggested recently for a nerve problem, but once the doctor saw they interreactions, she said I could not take it. Another is furosimide which I do take for high blood pressure. My kidney doctor does not like me taking it because of the renal failure, but if I don't my blood pressure goes up, & I start to retain fluids. He states that furosimide can exerbate renal failure.
All are different, & I don't have a reference for you to give you a list. Sorry. You could also type in the search box at the top of the page & see if you can find the info there too. There are a lot of references there about both of these conditions...
Since you sound like a student, and I rarely make a joke like this, the reason is you could kill the patient. Either by renal damage causing long term failure, or renal damage caused impaired healing. Same with hepatic.
Too much Tylenol, acetaminophen, is one of the leading causes for failure.
The rest of the advice is there for you by the others who wrote in. If you aren't a student, please take the information seriously and follow your physicians instructions carefully. The pharmacist is also responsible for this and are the back up for the physician order. That is why it is very important to always use the same pharmacy for all of ones prescriptions.
Good reading to you.
Hi, i worked as a veterinary nurse for many years and the same principle applies in humans. If you are taking medication that has the potential to cause liver or kidney problems, regular blood tests are/should be taken to monitor alb, alt, etc levels, and if they start rising then the medication should be discontinued or a plan to protect the organs should be put in place. This way you can prevent any issues arising in the first place. A specific diet can be used to help keep your liver and kidneys healthy also.
I just want to also add that most medications are processed and cleared from the body by the liver and kidneys so if there is extensive liver damage, the drug may never be processed and eliminated properly. If a person takes a regular daily dose and their liver (or kidneys for that matter, depending on which one is diseased) are not breaking down and clearing the medication, by adding subsequent doses you can have toxic amounts of drug accumulate in the blood because the drug is not being broken down and eliminated from the body. So in renal and hepatic disease, you want to know this ahead of time because one may want to make dosing adjustments, bloodwork to monitor drug levels in the blood, bloodwork to monitor kidney function/hepatic function tp prevent further damage etc. It is important to prevent further damage of course but the main reason to identify renal and hepatic disease before giving a drug is to know whether the drug will be safely broken down and cleared and how fast the body will do this so that you avoid toxicity.
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