I am a 48 year old female with a history of depression. Been on a slew of drugs (Prozac, Zoloft, Cymbalta, Effexor and most recently, 120mg of Fetzima with 15mg of Abilify. I have lost two children due to a rare metabolic storage disorder (my only kids) so not only is it depression, it is grief. I find that after being on these drugs for awhile, that I just become immune and the depression is just as bad so like an idiot, I stop taking them. The depression has gotten really bad again (not wanting to leave the house/shower) so I saw a new psych today who prescribed 50mg for imipramine for the first 5 days and then I increase to 100mg after that -- just 1x a day. Not that I am happy about the side effects that I am reading (oh joy - weight gain) -- but I have been doing my googling aoub the drug and see on various message boards about the negative effects of this drug. Has anyone truly gotten rid/improved their depression with Imipramine? Thanks
Back in the long past days as a teenager, the TCA antidepressants were about all that were available. I took Tofranil (imipramine) for years without any side effects and it was very effective.
Remember that only a very small percentage of users report side effects that last for more than the first few days to a week or so of starting the medication.
ALL drugs have side effects ~ look up aspirin or even Pepto Bismol ! The possible side effects would scare you to death but do you think twice about using them?
The only way to know is to try it... or live with depression.
Best regards and best of luck! Wildcat
I took this for many years and it was excellent. I've tried the newest drugs and they seem to peak pretty quickly and become ineffective after a couple of years. I wouldn't hesitate to go on it again. I had no side effects when I took it.
Best of luck to you and I'm so sorry for your loss
I have taken already many, many antidepressants and I must say Imipramine is good and makes on stable. Since April 2016 I am taking this drug now and went in this time through crisises. Stability occured at some time.
200 mg at once @ bedtime works very good for me. I could bear only 125 mg at once @ morning and day, because from 150 mg at day it makes very sleepy.
Taken at once is more effective than splitting and because it makes sleepy and drowsy, for me at bedtime is best if taking more than 150 mg at once.
Also the sexual side effects seem lesser severe than these SSRIs and not to speak Clomipramine, which were so severe that I changed to imipramine. Also the heart tachycardia is just little in my case.
Anyway I find it is a good AD.
I’m so sorry for your loss. Your profound grief is understandable and the depression must be unbearable. You are a brave person to keep going! You have my admiration and deep respect.
As far as the meds, I think I have taken everything you mentioned and I write on these board about the side effects and withdrawal symptoms that cripple many of us. On a non-med note, have you ever tried Brainspotting or EMDR for your trauma? Myself and 3 of my children do it and it has made a world of difference. Both CBTs help the brain manage the trauma and “put it away” so that the triggers and thoughts don’t happen as readily. There is lots of literature out there and at first I thought it was witchcraft (I’m a scientist) until it changed my life. Maybe you could look into it.
Best of luck to you!
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