If you mean Methadone it depends on the person. They usually start you out at a lower dose 2mg to 4mg and if you still feel like crap they will raise it until you feel better. If you are talking about Methamphetamine, Suboxone will not help with that. I hope this helps. Good luck to you!
If you are talking about methadone, you need to be off long enough to go into moderate withdrawals or you will go into precipitated withdrawal. Methadone is a long acting med and there has to be room on the receptor sites to accomodate the subutex or the 2 meds will kinda fight it out and you will suffer.
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