Vagifem 25 MCG
A placebo-controlled comparison study was done in the U.S., in which 230 patients were randomized to receive either placebo, Vagifem, or 10µg estradiol vaginal tablets. Patients inserted one tablet intravaginally each day for 14 days, then one tablet twice weekly for the remaining 10 weeks. All patients were assessed for vaginal symptoms. Vagifem® was superior to placebo in the relief of symptoms of the dryness, soreness, and irritation associated with atrophic vaginitis. This change of symptoms was seen at Week 7 and was maintained throughout to Week 12.
From the results of this study you may need to continue treatment with Vagifem for around 6 to 8 weeks before you notice any relief of your symptoms.
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