I was taking this drug and one ankle swelled to twice it's size. When I stopped taking the drug, the swelling subsided. My doctor said that I should not stop taking the medicine, so I started it again. After 3 days my ankle swelled up again to twice it's size. It was deformed. It this the from a type of renal problem? I have no other problems with edema at all. Only when I take this medication. My GI doctor didn't seem to have any response. thanks!