I also take bupropion 300xl once daily. Now my anxiety and panic is returning. Any suggestions? I am wondering if going back on Pristiq, along with Topamax instead of Bupropion will be better. Pristiq seemed to stop the panic and anxiety, but caused weight gain as did cymbalta. Should I also up the Topamax from 100 mg. to 150 or 200 mg?
I am presently taking Pristiq and bupropion at the same dosage as you were. I have been able to lose 25 pounds over the past few months but I have really been trying hard to reduce my calories. I like the combo of Pristiq with the bupropion very much. I have tried Topomax for weight loss when I was on Cymbalta but to be honest it didn't really help. It wasn't until I really started watching my calorie intake that I began to lose the weight.
You are on a low dose of Topomax. As you are using it for an off label reason, it is difficult to say what the appropriate dosage might be. Everyone is different, one size doesn't fit all, as the saying goes. I hope the Topomax works for you. If the anxiety and panic are returning than going back on the Pristiq with the bupropion and Topomax maybe the answer.
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