... flu-like symptoms had me down for at least 2 days or more, so after 6 months, I have switched to Copaxone. My question is does anyone else get hives after they inject the med, and 4 hours later have fever, chills, headache, that goes away by the end of the day?? I am new to this, started it a week ago, and the past three days, ended up with these symptoms. maybe not related to the meds, but very odd