Those two will compete for the same receptors, and the methadone should win. If there are receptors that are not being used by the methadone you may feel the oxys. Although the two will probably not interact in a bad way, mixing the two is an addictive behavior. Be carefull!!!
- Methadone Information for Consumers
- Methadone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methadone (detailed)
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