... by use of suitable polymer matrix.for this i need newer drug molecule not available in sustained release form with protien binding more than 80%,molecular wt less than 500 and having les half life.sfor this i have selected anti psycotic class... please suggest me any new drug molecule from this or other class not available in sustained release form
Hi - I am not sure if this will help but have you considered Trifluoperazine.
It is a first generation anti-psychotic. It is 91-99% protien bound. It's molecular weigh of 407. No extended release is available that I know of, but I am not sure of it's specific half life
Brian PharmD Candidate
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