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I just filled a RX for Vytorin and it is a product of Singapore, why and it is safe?

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Anonymous 5 Jul 2010



Second:Vytorin receives FDA approval amid controversy over its role
FDA approval had finally arrived for VytorinTM, the highly anticipated simvastatin/ezetimibe combination from Merck/Schering-Plough. Although both components of the drug combination are available separately, the combined pill is expected to play a significant, though somewhat controversial, role in the enormously successful cholesterol-lowering marketplace.
This was approved a long time ago.

What Is Vytorin?

Vytorin (ezetimibe/simvastatin) is a prescription medication used for high cholesterol and high triglycerides. It is a combination of two medicines: ezetimibe (Zetia), which is a cholesterol absorption inhibitor, and simvastatin (Zocor), which is part of a class of drugs called HMG-CoA reductase inhibitors (more commonly known as a statin).

What Is Vytorin Used For?

Vytorin (ezetimibe/simvastatin) is a prescription medication that has been licensed to treat several conditions. These uses for Vytorin include:

Treatment of hyperlipidemia, including:

High total cholesterol
High LDL cholesterol ("bad" cholesterol)
High triglycerides
High apo B cholesterol (another "bad" cholesterol)
Low HDL cholesterol ("good" cholesterol)

Treatment of heterozygous or homozygous familial hypercholesterolemia (a genetic form of high cholesterol).

Who Makes It?

Vytorin is manufactured by Merck/Schering-Plough Pharmaceuticals (MSP).

Vytorin: What Should I Tell My Healthcare Provider?

Talk to your healthcare provider prior to taking Vytorin (ezetimibe/simvastatin) if you have:

Liver disease or liver failure
Kidney disease or kidney failure
Any allergies, including allergies to foods, dyes, or preservatives.

Also, let your healthcare provider know if you:

Are of Chinese descent
Are pregnant or thinking about becoming pregnant
Are breastfeeding
Will be undergoing a procedure or surgery
Drink alcohol frequently.

In addition, tell your healthcare provider about all other medicines you are currently taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Vytorin Precautions and Warnings
Some precautions and warnings to be aware of with Vytorin include the following:

Vytorin can interact with certain medications (see Vytorin Drug Interactions).

If you are an alcoholic or drink alcohol frequently, discuss this with your healthcare provider prior to starting Vytorin. Alcohol can affect the way the liver works, indirectly affecting the effects of Vytorin.

Statins have been known to cause an increase in liver enzymes. Therefore, it is recommended that you have a blood test to check your liver function before starting Vytorin and then again several months after treatment has started. .

Rhabdomyolysis (the severe breakdown of muscles) and other serious muscle problems have rarely been reported with Vytorin and other statins. Contact your healthcare provider immediately if you experience any muscle pain, weakness, or tenderness, especially if accompanied by body aches or a fever (see Vytorin and Muscle Pain).

Studies have suggested that Chinese people may be at a higher risk for serious muscle problems when simvastatin (one of the components of Vytorin) is combined with niacin (see Niacin and Vytorin for more information).

Vytorin is a pregnancy Category X medicine, meaning that the drug could potentially cause harm to your unborn child. The safety of Vytorin in pregnant women has not been established. Therefore, if you become pregnant while taking Vytorin, talk to your healthcare provider immediately

If you are nursing, it is not known whether Vytorin passes through your milk. Therefore, if you are taking Vytorin, ask your healthcare provider whether to stop nursing or to discontinue your Vytorin.

I hopes this helps..from a caring individual

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