I'm not sure which suppositories you used ... but even if you weren't relieved it does not indicate a serious problem.
However, have you been constipated for a long time? What other medicines have you used to relieve constipation? Are you on any other medication? When you don't have constipation do you suffer from diarrhea? All of these and a few other questions need to be investigated before you cn say if there is a major problem.
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