Isuffer from servere osteoarthritis ans infamation where my whole body swells. Took nsaids for over 20 yrs developed pancreatitis in 2007 had to stop because of gastro-intestinal problems now have gerd. Am not sure methtrexate will be safe for me to take. Could use some advice please I ALSO SUFFER FROM LYMPHODEMIA SERVERE SWELLING IN LOWER EXTRIMITIES AND WRISTS AND FINGERS.