Also take Cranberry tabs, Pepcid. Do I need to worry about any interaction because of the amlodipine that I am going to be taking? It says to check about any interactions with your medication so I am checking. ;-)
Tegretol, Keppra, Diazapam, Coreg Elavil and Vitamin C - any drug interactions with Amlodipine?
- 21 Jul 2010 by Has2Bprfct
- 22 Jul 2010
- coreg, elavil, keppra, pepcid, tegretol, vitamin c, vitamins, high blood pressure, seizures, epilepsy, amlodipine, cranberry, interaction
Hello, I have done aninteraction checher on this site.
Please read the following important information
Interactions between your selected drugs
amlodipine ↔ carvedilol
Applies to: amlodipine, Coreg (carvedilol)
MONITOR: Additive reductions in heart rate, cardiac conduction, and cardiac contractility may occur when calcium channel blockers are used concomitantly with beta blockers, particularly in patients with ventricular or conduction abnormalities. While this combination may be useful and effective in some situations, potentially serious cardiovascular adverse effects such as congestive heart failure, severe hypotension, and/or exacerbation of angina may occur. The proposed mechanisms include additive slowing in AV conduction, reduced cardiac contractility secondary to beta-blockade, and decreased peripheral vascular resistance secondary to calcium channel blockade. In addition, some calcium channel blockers may inhibit the CYP450 metabolism of hepatically metabolized beta blockers, resulting in increased serum concentrations.
MANAGEMENT: Close clinical monitoring of patient hemodynamic response and tolerance is recommended if a calcium channel blocker is prescribed with a beta blocker, and the dosage of one or both agents adjusted as necessary. The same precaution should be observed when beta blocker ophthalmic solutions are used, since they are systemically absorbed and can produce clinically significant systemic effects even at low or undetectable plasma levels.
carbamazepine ↔ amlodipine
Applies to: Tegretol (carbamazepine), amlodipine
MONITOR: Some calcium channel blockers may reduce the CYP450 3A4 hepatic metabolism of carbamazepine. Carbamazepine serum levels and risk of toxicity may increase. In addition, carbamazepine may reduce the bioavailability of some calcium channel blockers by induction of CYP450 3A4 metabolism. Serum levels and activity of calcium channel blockers may be decreased. Data are available for verapamil, felodipine, and diltiazem.
MANAGEMENT: If alternative therapy is not appropriate, close observation is recommended for altered efficacy and safety of both drugs whenever either is added, discontinued, or changed in dosage. Patients should be advised to report worsening of their symptoms and signs of carbamazepine toxicity (nausea, visual disturbances, dizziness, or ataxia) to their caregiver. Dose adjustments may be required.
carbamazepine ↔ levetiracetam
Applies to: Tegretol (carbamazepine), Keppra (levetiracetam)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
carbamazepine ↔ diazepam
Applies to: Tegretol (carbamazepine), diazepam
MONITOR: Some antiepileptic agents such as carbamazepine and phenytoin significantly reduce the effect of oral midazolam. The mechanism may be due to enhanced gut and liver metabolism of midazolam (via CYP450 3A4 enzyme induction by carbamazepine). Parenteral midazolam is not likely to be affected. Other oral benzodiazepines metabolized by the 3A4 isoenzyme may interact similarly.
MANAGEMENT: Patients receiving this combination should be monitored for clinical response. Alternative oral sedative hypnotics may be preferable in patients receiving carbamazepine.
diazepam ↔ carvedilol
Applies to: diazepam, Coreg (carvedilol)
MONITOR: Many psychotherapeutic and CNS-active agents (e.g., anxiolytics, sedatives, hypnotics, antidepressants, antipsychotics, opioids, alcohol, muscle relaxants) exhibit hypotensive effects, especially during initiation of therapy and dose escalation. Coadministration with antihypertensive agents, in particular vasodilators and alpha-blockers, may result in additive effects on blood pressure and orthostasis.
MANAGEMENT: Caution is advised during coadministration of these agents. Close monitoring for development of hypotension is recommended. Patients should be advised to avoid rising abruptly from a sitting or recumbent position and to notify their physician if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia.
No other interactions were found between your selected drugs.
Note: this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.
Other drugs that your selected drugs interact with
* amlodipine interacts with more than 200 other drugs.
* diazepam interacts with more than 300 other drugs.
* Coreg (carvedilol) interacts with more than 400 other drugs.
* Keppra (levetiracetam) interacts with more than 100 other drugs.
* Tegretol (carbamazepine) interacts with more than 400 other drugs.
* Vitamin C (ascorbic acid) interacts with more than 20 other drugs.
Take care and best of luck
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