... Compared to the other drugs I was on (Dilantin, Tegretol to name a couple), I feel as close to normal as possible and I have been well controlled. My husband and I were always concerned with possibilities of birth defects due to my meds. However we were told and understood that Lamictal's research did not show to have as significant birth defect rates as "older" meds did. Of course, we took into account the fact that it was a new med therefore did not have adequate longitudinal evidence. Anyway, we have a healthy 5 year old and now would like to have another child. Recently my neurologist informed me that reports have come out that Lamictal is proven to have an increased chance of birth defects (shocking... hint of sarcasm). Now she said that Keppra has less recorded birth defects than Lamictal. Keppra is also 5 years younger and, just like Lamictal in previous years, does not have long-term data to support otherwise. My predicament is... should I change my Lamictal which allows me to live a "comfortable" life with minimal side effects and is proven over a long period of time to control my seizures? Or do I change to Keppra which isn't guaranteed to offer me piece of mind and puts me at risk of seizures which could have a detrimental effect on my family and health... just so reduce my chances of birth defects? I am also concerned for my quality of life. I use to be on multiple "older" meds that put me in a haze for years and I DON'T want to go back there. I have researched for hours for actual statistics but haven't come up with a whole lot. If there is there anyone who can offer some advice... or anyone who has experienced side effects from Keppra that you could warm me about would be greatly appreciated. Thank you :)
Hi, i've done a bit of research, and it seems the main concern of lamictal in child birth is the chance of the child being born with a cleft palate of cleft lip. Research shows that the chance of this occurring are 8.9 in 1000. In most cases a child born with cleft palate or lip can have this surgically corrected quite easily. I completely understand your concern. All i would consider is that, although keppra has a lower risk factor, who is to know that these statistics won't change in the future with more use when doctors have more patient information? Also, the risk of swapping meds and you having a seizure whilst pregnant could also mean a very real risk for your unborn child as well as yourself obviously. It is a decision you'll have to make with your partner but hopefully others will reply to your question with their experiences.
I would definitely stay with the lamictal as it seems to be working for you and obiviously kept you stable even during your pregnacy. Don't try to fix what isn't broken. You have a healthy child. Pray that the next will be too. The odds of problems are slightly higher with any one on anti seizure meds but they also happen to women who are not on any meds. I think you are really saying you are failry comfortable with the Lamictal and not comfortable switching. Count your blessings and follow your heart.
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