I have been on it for a day. I was taking effexor for 1 week and it was great! I went to a new pschiatrist and she said Bipolar people should not be on anti depressants. I feel so bad from the first day, I have a headache and I had a horrible morning with this med. I have been crying all morning, I did not go to school because I feel so bad. I just want my effexor back and I know my doctor is a good one so I trust her, but I am not sure if I trust this med. I gained 20 lbs before the effexor and I it was awful. I don't understand why she says bipolar ppl cant take it when I see all of you out there on different types, and sometimes more than one? If anyone has any input I would really be glad to here it. Thanks.