I have been on Atripla for 3 years now and have to say that the only side effects are very vivid dream that I can handle no problem, but my main concern is that for 4 hours after I take it I just feel so bad. I have no energy, my head is spinning and I have just a general sense of nausea. Now don't get me wrong, this medication has saved my life I will continue to use it until I am told to change by my doctor. Does anyone have any advice other than take on an empty stomach and at bed time. I should point out that I am a flight attendant so my hours are pretty erratic. I always take mine at 3pm so if I am going out in the evening the effects have worn off by then and I also find that where ever in the world I am I never have to get up in the middle of the night to take it, it is either morning or evening. Thanks in advance for any help