... of my life. First major episode was when I was 14 years old and I am now 62 . Have been on almost all of the early antidepressants of the 1970's and 80's as well as lithium and none of them helped the depression. Finally I opted for ECT treatments which helped somewhat. Have had many years of talking therapy with several therapists with different approaches. Now under another psychiatrists care have been on paxil for over 9 years, the last 3 years on 75mg paxil cr, as she had to keep increasing the dosage to keep my symptoms in check. However, for the last 6 months or so the paxil seems to be losing its effectivness as I am suffering from a constant sense of anxiety. Can this happen with the ssri's and pazil in particular, where it once worked well and then loses its effectivness? Is there another alternative ssri or snri that might be a good substitute for the paxil? I am also on Deplin 7.5 mg(folic acid) and 4 grams of fish oil per the doctor as well. Thank you for any help
Ask your doctor about a mood stabilizer such as Abilify. I had anxiety and was still somewhat depressed while taking Effexor XR. I asked my doctor about Abilify. We tried it. It was amazing. It took a few weeks to start working but the results were amazing and still are amazing. It also helped with some of my anxiety. I'm also on Xanax for severe anxiety and Panic Attacks as well as Agoraphobia. So if you experience more severe anxiety you might benefit from a benzodiazepine. But talk to your doctor about trying abilify. It might be an option for you. I hope this helps a little. Good Luck and Happy Holidays!
I was on Paxil for many years and the same thing happened to me, it was losing its effectiveness. They can peeter out as my Dr. confirmed. I had also gained weight and wanted something that wouldn't make me feel so sedated, so she put me on Wellbutrin. It helped the depression but I feel that its not working as well as Paxil and I am very emotional on it. Also, in the beginning you can get more anxiety. I hope this helps and that you find something that works for you!
I have also been diagnosed with Major Depression, I have been on numerous medications and had ECT treatment (which I do not recommend)
I have been taken an older drug they used for major depression called PARNATE it's a MAOI and I have been on it for 11/2 yrs. It is the best thing that I have ever been on. I'm on the maximum dose of 60mg per day. I started out slow because if you start too fast it messes with your blood pressure. I can not say enough good things about it. When I was on Paxil it made me more depressed. I would list my previous meds but there are too many. Until I tried the MAOI med, I would be ok for a little while then right back to being depressed. cathyannbrad62
- Paxil Information for Consumers
- Paxil Information for Healthcare Professionals (includes dosage details)
- Side Effects of Paxil (detailed)
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