I was diagnosed with a type of peripheral neuropathy from breaking my 5th metatarsal (foot), it was not set or pinned, and failed to heal correctly, entrapping/damaging the nerves. I am fighting to maintain circulation to keep the foot, and the pain was unbearable. Already suffering 23 yrs Multiple Sclerosis, my meds just to handle pain include Methadone, Duragesic Patch, Klonopin, Indocin, and Lyrica. A trial on Lyrica was hopeful, I had significant pain relief after a few days even and greatly increased mood, however I could not think, read, drive, or even add 2 + 2. A trial of Gabapentin for MS nerve pain in 2001 was discontinued to due inablity to manage the side effects (I was a graduate student at the time).