That off and on for ten years or more
Yes there are long term effects.
Physical and psychological dependence may occur with the long-term use of phentermine.
A withdrawal reaction, which includes excessive drowsiness fatigue, tremors and depression may occur.
You should consider seeking help to quit phentermine if you think you may be dependent.
See: https://www.drugs.com/sfx/phentermine-side-effects.html for more information - scroll down to drug abuse and dependence.
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