long period of use. I took Niaspan for almost two years with a gradually increasing dose. The side effects were tolerable until I reached the 2000 mg dose. At 2000 mg, I had decreased appetite and unintentional weight loss; and, when I complained to the prescribing doctor, she discovered my liver enzymes had gone up from low-normal to abnormal and my blood sugar level had gone up from high-normal to abnormal. I was told to stop Niaspan. No one has been able to tell me what withdrawal effects will occur after stopping Niaspan. Has anyone had Niaspan or Niacin withdrawal reactions or withdrawal side effects that they can share? Thanks.