I have been on it now for over 5 years, and I am starting to struggle a bit. It was an all out miracle when I first started on it. My life changed with in a few months. I felt amazing and started having a life. The last 6 months or so I have been having a harder time and battling some anxiety. Nothing near as bad as before lex, but worse than it's been since I started. I was just curious if anyone else noticed it becoming less effective over time?