My blood levels have been high lately and my doctor added januvia to the metorformin and glyburide that I have been taking, but didn't seem to do the trick. So then he added actos. I have been on actos before and experienced severe weight gain. I am a little uncomfortabe taking 4 medications for my diabeties. He keeps adding medications. I feel he should take away the januvia since it didn't work or try different combinations.