pain, diabetic nerve pain, osteoarthritis.
Hey Kansas Gal,
After reviewing the literature, nortriptyline is metabolized by the liver and excreted by the kidneys. There were no studies done on dose adjustment for kidney impaired patients. Nortriptyline does help with neuropathic pain and depression. You would have to have your blood levels monitored frequently. I recommend you speak to your kidney doctor about this medication before taking.
There are other medications you may want to investigate such as Lyrica. There is much information available on adjusting dosage for the renally impaired patient. You can read this by going to the following and scrolling down the page: https://www.drugs.com/dosage/lyrica.html
Your dosage of Lyrica should be adjusted according to your creatinine clearance levels and whether you are receiving dialysis.
Hope this has helped some and best wishes,
Hi, although drug information doesn't suggest any side effects will occur that can exacerbate renal disease, one study of nortriptiline in subjects with renal disease/failure indicates that it should be used with caution. I assume you are considering it to help with feelings of depression? Have you discussed this with your healthcare provider?
- Nortriptyline Information for Consumers
- Nortriptyline Information for Healthcare Professionals (includes dosage details)
- Side Effects of Nortriptyline (detailed)
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