I am an "emergency" newbie in the sense that I have been asked by someone without computer access or other research capability to quickly find out if Zoladex vs castration in a sixty something male ( ex-brother-in-law) has any severe downsides. His prostate cancer metastisized into his hip... pretty far along. Docs in his rural community in New Mexico have gottne some sorta handle on that, and he is walking without a cane now, gaining weight, etc, but still in deep doodoo.

Question therefore has to be based on skimpy info, but is there any real severe downside to Zoladex, including ostesporosis, that hee should be worried about? Thanks for any quick replies