I am a health professional with a relative who has been prescribed this medication and the literature says the efficacy has not been determined, would this mean he is in a clinical trial?? Just curious, the last posted review is from feb 09 (10 months ago)--aren't there any more recent comments?? He has been experiencing esophageal discomfort, nausea, vomiting, explosive diarrhea and unusual weight gain which is odd with these symptoms.