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I am a 70 yr old female.Taking pristiq,abilify,bupropion,zolpidem-tartate.Too much med?

Responses (2)

LaurieShay 8 Apr 2011

Hey dongraven,

Are you asking if you are taking too many meds? I also take Pristiq, Abilify and bupropion. I have had great success with this combination of medications. I have not taken Ambein (zolpidem) for insomnia.

I personally don't think this is too much medication especially if you are under the care of a qualified doctor. Is this combination of medication working for you?

Best wishes,

Laurie

dongraven 10 Apr 2011

Thanks Laurie,
Not working yet.It has only been 10 days.
How long did it take for you?

LaurieShay 10 Apr 2011

You started all these meds just 10 days ago? Or you started the Pristiq just 10 days ago or what? It will take the antidepressants like Pristiq and bupropion upwards of a month or so to feel the full effects. The Abilify doesn't take quite that long.

dongraven 10 Apr 2011

Hi Laurie,
Pristiq replaced Lexapro which I had been taking for two yrs.with buproprian
and abilify,Lexapro did not seem to be working anymore.

LaurieShay 10 Apr 2011

Ok, I understand now. It will take up to a month or so to feel the full effects of the Pristiq. Good luck!! I have had great success with Pristiq and would highly recommend it.

dongraven 10 Apr 2011

Thanks Laurie,
Your input is helpful.I actually feel worse instead of feeling better.I am trying to be patient.

PillboxHat 1 Jan 2018

That a lot of drugs, especially for someone 70 years old, in my opinion. If the original problem was depression, and the first antidepressant did not help, many doctors would have advised you to stop taking it. It looks like your doctor decided to add a new drug without stopping the old one. Given all the side effects, it is hard to support the idea that one's life will be improved by four drugs.

Abilify can cause extreme agitation. Also wright gain and metabolic syndrome.

Bupropion can increase the odds of a seizure. Also, insomnia and weight loss.

Pristiq can difficult to stop taking.

The interaction-checker on this site says there are two major drug interactions and two moderate ones:

Major
Applies to: bupropion, Abilify (aripiprazole)
Talk to your doctor before using buPROPion together with ARIPiprazole. Combining these medications may increase the risk of seizures, which may occur rarely with either medication.

In addition, buPROPion can increase the blood levels of ARIPiprazole, which may increase other side effects.

You may be more likely to experience seizures with these medications if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should avoid or limit the use of alcohol during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Major
Applies to: bupropion, Pristiq (desvenlafaxine)
BuPROPion may rarely cause seizures, and combining it with other medications that can also cause seizures such as desvenlafaxine may increase that risk.

You may be more susceptible if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate
Applies to: bupropion, zolpidem
Excessive use of zolpidem, or abrupt discontinuation following long-term use, may occasionally trigger seizures in patients taking buPROPion. Talk to your doctor before using these medications together if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate
Applies to: zolpidem, Abilify (aripiprazole)
Using zolpidem together with ARIPiprazole may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating.

Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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