my msir 30mg and fentanyl 100mcg. patch i have been on same dosage for about 1-1/2 yrs. lately the msir isnt helping for breakthrough. if i ask pain dr. to increase msir dosage do you think he will, or say i have to lower dose for a while to lower my high tolerance to msir. i dont want to hurt anymore than i am allready, but sometimes i have to take two msir 30mg to make pain bearable, if i walk for short while.maybe there is a another drug to replace msir