My Endocrinologist prescribed Hydrelazine 75mg twice per day, approximately 18 months ago there was a shortage and my Pharmacist changed the scrip to Hyperfen and accidently increased the dosage to 150my twice a day. Since taking this increased dosage I have been extremely tired, no motivation etc. My Dr sugested that I see a Psycologist who diagnosed depression and put me onto 50mg of Cipralex, I have been on the coctail for 15 months with no improvemaent whatsoever. Would the increase overdosage combined with the antidepressant cause this.