I am having insulin secretion excess in blood level hyper insulin 37 in faster insulin level in lab result please tell drug name to control insulin in over insulin level in blood
I don't know if you are prediabetic or a diagnosed diabetic. From Medscape:
"Insulin secretion may be altered by various mechanisms. Oral diazoxide inhibits pancreatic secretion of insulin, stimulates glucose release from the liver, and stimulates catecholamine release, which elevates blood glucose levels. Octreotide is a peptide with pharmacologic action similar to that of somatostatin, which inhibits insulin secretion. KATPs (ATP–sensitive potassium-dependent channels, composed of the SUR1 and Kir6.2) are inactive in diffuse disease. These channels initiate depolarization of the beta-cell membrane and opening of calcium channels. The resultant increase in intracellular calcium triggers insulin secretion. Calcium channel blockers block the activation of these calcium channels, decreasing insulin secretion. Nifedipine is the only calcium channel blocker that has been used for the treatment of hyperinsulinism in humans and appears to be clinically ineffective.
First-line treatment. PO diazoxide (Proglycem) opens KATP channels and inhibits insulin secretion. The IV preparation (Hyperstat) is not used in hyperinsulinism.
Somatostatin analogue, activates G-protein K channel. Hyperpolarization of beta cell results in inhibition of calcium influx and insulin release. Octreotide also used for acromegaly, carcinoid tumors, and VIPomas.
"Nifedipine (Adalat, Procardia)
Blocks calcium channels and insulin release. Also used to treat hypertension and angina."
End of Medscape information.
For a different approach:
Medications that reduce insulin resistance include biguanides, which improve your body's sensitivity towards insulin, and thiazolidinediones, which have insulin-sensitizing and antihyperglycemic effects.
These drugs work primarily by increasing the amount of glucose taken up by muscle and fat cells. They are used in type 2 diabetes with insulin resistance. I'm adding this information since your high insulin level can be due to insulin resistance.
Here's what's good about TZDs:
They are quite effective at bringing down elevated blood glucose levels.
They tend not to lose their effectiveness as quickly as most other medications used to lower blood glucose.
Here's what's bad about TZDs:
They cause weight gain.
They increase the risk of heart failure.
They increase the risk of osteoporosis.
Depending on the particular TZD, they may adversely affect your cholesterol levels.
These are the two available TZDs:
Because of the risk of adverse effects of TZDs - and in particular, the perceived risks of rosiglitazone - TZDs are being used less and less often.
Riomet, which is liquid metformin
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 12 Jan 2010 • 1 answer
Posted 29 Jun 2011 • 1 answer
Posted 16 Sep 2013 • 1 answer
Posted 30 Aug 2016 • 1 answer
Posted 5 Oct 2016 • 0 answers