Hydroclorothiazide (or HCTZ) is a diuretic drug (sometimes called "a water pill"). It wont affect clotting at all. There are no contraindications for taking this drug when you have a history of blood clots.
If you are taking Warfarin then you will need to be tested more at the beginning of your taking this drug as it may cause higher plasma levels of clotting factors and decreased the anticoagulant effect of the Warfarin.
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