en severe vomiting. We dont take any medications at same time as ropinirole. We go to bed and within 30 minutes Nausea hits, then vomiting. It takes at least an hour to have any effect. By then it's out of our system from vomitting. Why the vomiting and can you suggest another drug for RLS without the nausea and vomiting and relieves our RLS much faster. ropinirole takes at lrast an hour to work, but in our case it doesnt work at all. We hate that med for RLS.