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How do you use Kevzara?

Answers (1)

Official Answer by Drugs.com 5 Jul 2017

Kevzara (sarilumab), an injectable interleukin-6 receptor (IL-6R) antagonist from Regeneron and Sanofi, is used to treat moderate-to-severe rheumatoid arthritis. It is intended for patients who failed or cannot tolerate at least one other disease modifying antirheumatic drug (DMARD). Kevzara may be used alone as monotherapy or in combination with methotrexate (MTX) or other conventional DMARDs.

In the MOBILITY study, treatment with Kevzara plus MTX improved physical function and demonstrated significantly less radiographic progression of structural damage compared to placebo plus MTX.

Common side effects included neutropenia, increased liver enzymes, and injection site redness, among others.

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