Online, I have been reading that 50 mg is the recommended dosage, but that some people take more. Then it got confusing. It said that more than 50 mg was still useful but no more effective. If this is the case, why are some people put on higher doses? Did I misinterpret this information?
Everyone is different and as a result can respond differently to medication doses. Recommended doses are guidelines for professionals to use their judgement based on patient response and condition being treated etc.
This from the fda monograph for Pristiq.
"... The recommended dose for Pristiq is 50 mg once daily, with or without food.
In clinical studies, doses of 50-400 mg/day were shown to be effective, although no additional benefit was demonstrated at doses greater than 50 mg/day and adverse events and discontinuations were more frequent at higher doses."
Doctors probably try higher doses to see if they can get a better response but as shown above this is not usually the case.
- Pristiq Information for Consumers
- Pristiq Information for Healthcare Professionals (includes dosage details)
- Side Effects of Pristiq (detailed)
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