My daughter has been on 30mgs of Cymbalta for about 7 to 8 weeks. She was doing well until recently. Her psychiatrist increased her dose yesterday to 60mg due to her being more irritable, fustrated and more depressed like. When we started 30mgs it took about a week to notice a difference and then about 3 to really kick in. Will it be the same with the dose increase or should we notice a difference sooner? I am hoping sooner since she seems to be in emotional pain.