My daughter is 15 and after being on 30mg of Cymbalta for 8 or 9 weeks and at first doing quite well, she had a setback and her doctor increased her dose to 60mg, 19 days ago. While we have seen some slight improvement on the 60mg, it is not like the vast improvement we initially saw on the 30mg. She suffers from depression/anxiety/panic disorder. Cymbalta so far is the only medication that has helped at all. I am just wondering if we need to wait the full 4 to 6 weeks to see an improvement or should it be sooner?