Please help. I see that lots of people are having trouble sleeping on pristiq but I dont see insomnia listed as a side effect. I have been on pristiq for 5 days and find myself awake at 3:00am every morning. Also... does the side effect of loss of appetite eventually go away? I am a very small person to start with and dont want to loose any more weight. I guess what I need to know is... do the side effects go away after 4-6 weeks or do they continue on. I know it takes the med 4-6 weeks to start working. This is my first try at an antidepressant/anxiety med and feel really lost and nervous about taking an antidepressant. Thanks so much.