I'm not sure how long it'll take for Ivermectin to kill headlice. It most likely needs to be applied several times to target the headlice at a stage where it kills it.
Formulations containing 1.0, 0.5 and 0.25 percent ivermectin were found to be 100 percent effective in killing newly hatched lice following 10 minutes of exposure. The topical formulation was also more effective than 0.5 percent ivermectin alone, indicating that the mixture may allow the ivermectin to penetrate more easily into the lice.
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