I have trouble digesting pills and getting their full affect) and Effexor. The Effexor I was able to chew so I could digest it. The company that made the liq. quit making it, the only other liq close to what I need is Zoloft. I gained about 40 pounds since I was put on the Effexor 3 years ago. I was on Zoloft many years ago and it worked great, and I don't remember being overweight. I hope I can lose the weight. I have been on the Zoloft 1 week and being liquid I hoped it wouldn't take long to get into my system, but I am very nervous, depressed and just not thinking "good thoughts", I'm grumpy and stressed. Any suggestions? JC