I am detoxing from OpanaER. It is very hard, and feels like a big test of patience and endurance. My body is so addicted to this drug that I have incredible withdrawal between my three daily doses! I get incredible anxiety both during the period before the next dose, and basically throughout this entire process! I wake in great pain some days. This lasts until I can get the pain under control with the next does. And, I get really bad breakthrough pain which is caused by my body's cravings, probably MORE than the pain under the medication. I am down from Opana ER 40mg 3 times/day to (what I am praying I can do today) 25mg Opana ER!!! Can you help me deal with the anxiety? Thanks so much! Marie