Hi, they all work slightly differently, what kind of pain are you wanting to treat? More information will make it easier to advise you...
You can take a combination of medications, for example, if the Tramadol isn't dealing with the pain on it's own, you can take Paracetamol and/or Ibuprofen with it quite safely. Please don't take Tramadol with Cymbalta, it could make you very ill. Write back with more info' so we can advise better
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