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Hi,what is relation between leishmlania, allopurinol and leishmania growth, uric acid?

Responses (1)

suzanne66 29 Aug 2011

This from http://emedicine.medscape.com/article/998804-overview
Allopurinol inhibits xanthine oxidase, the enzyme that synthesizes uric acid from hypoxanthine. Reduces the synthesis of uric acid without disrupting the biosynthesis of vital purines. Not effective as monotherapy for leishmaniasis.

sara2010 29 Aug 2011

Hi,
thank you for your answer
but I think that the Leishmania parasite has no enzyme xanthine oxidase

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