All medicines have side-effects. You can view accurate and complete lists of side-effects for sotalol and cardizem here:
A potentially serious drug-interaction exists between sotalol and cardizem. Together they can cause an increased reduction in heart rate, cardiac conduction and contractility which could lead to congestive heart failure, hypotension or worsening angina.
MANAGEMENT: Close clinical monitoring of patient hemodynamic response and tolerance is recommended if these agents are used together, and the dosage of one or both agents adjusted as necessary. Patients should be advised to promptly report any symptoms including fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat.
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