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Hi,is there any problem when I take postinor(levonorgestrel)while am still on Yasmin?

Responses (1)

Rajive Goel 3 Sep 2010

Interactions between your selected drugs

No results found - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Other drugs that your selected drugs interact with

* levonorgestrel interacts with more than 100 other drugs.
* Yasmin (drospirenone/ethinyl estradiol) interacts with more than 400 other drugs.

Interactions between your selected drugs and food: ethinyl estradiol ↔ food

Applies to: Yasmin (drospirenone/ethinyl estradiol)

The coadministration with grapefruit juice may increase the bioavailability of oral estrogens. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall induced by certain compounds present in grapefruits. In a small, randomized, crossover study, the administration of ethinyl estradiol with grapefruit juice (compared to herbal tea) increased peak plasma drug concentration (Cmax) by 37% and area under the concentration-time curve (AUC) by 28%. Based on these findings, grapefruit juice is unlikely to affect the overall safety profile of ethinyl estradiol. However, as with other drug interactions involving grapefruit juice, the pharmacokinetic alterations are subject to a high degree of interpatient variability. Also, the effect on other estrogens has not been studied.

Read more: https://www.drugs.com/interactions-check.php?drug_list=1461-0,947-2536#ixzz0ySaOQitL

lizzygaks 3 Sep 2010

So what do you advice me to do?should i take or shoud i not take?

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