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What are the indications for Pneumocystis Pneumonia Prophylaxis in non HIV patients?

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suzanne66 23 Aug 2009

Pneumocystis Carinii Pneumonia is a pneumonia caused by the fungal organism Pneumocystis carinii (now renamed Pneumocystis jiroveci). This organism is common in the environment and does not cause illness in healthy people.
However, Pneumocystis carinii can cause a lung infection in in people with a weakened immune system due to any of the following conditions:
Cancer
Chronic use of corticosteroids or other medications that affect the immune system
HIV/AIDS
Solid organ or bone marrow transplant
PCP was a relatively rare infection before the AIDS epidemic. Before the use of preventive antibiotics for PCP, up to 70% of people in the U.S. with advanced AIDS would develop PCP.

Preventative therapy is recommended for:

AIDS patients with CD4 counts below 200
People on chronic high-dose corticosteroids
People who have had previous episodes of PCP

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