Hello to all fellow chronic pain sufferers , I am a long term chronic pain case . I have degenerative disc and back disease , , have failed back surgery syndrome , spinal fusion , loss of fluid between two discs, disc bulge , nevre damage , stenosis , i also have a spinal cord stimulator implant in my tummy . At this stage i have tried every drug there is ,.currently taking ketamine and have just been prescribed duralgesic patch 100 , have applied first patch just now , can anyone tell me how long will it take to work it's way through my system and give pain relief ,I have been on these patches before but it was about 3 years ago and can't remember the details , I'm sure many of you can identify with the issue of memory loss due to so many meds any answers would be greatly appreciated ,Lisa