My Chemist printout says it can be "deadly"! Why guys?
It turns out that grapefruit juice is one of the foods that is most likely to cause problems with drugs such as Xanax due to the fact that it is metabolized by the same enzyme in the liver that breaks down many drugs. The cytochrome P-450 3A4 enzyme breaks down grapefruit juice into useful components for body, just like it breaks down dozens of medications. When the system is overloaded, the grapefruit juice can "swamp" the system, keeping the liver busy and blocking it from breaking down drugs and other substances.
While the liver devotes its resources to grapefruit juice, the medication could build up to dangerous levels. This is also true with certain antacids, not tums, but the other ones - forgot the chemical name... starts with a "C"
I think that in certain cases, alcohol can act in this way, as the liver puts its focus on breaking down the alcohol first, and then certain medications second - or in other cases, it simply increases the effects of the drug. Totally depends. I read this quite a while back, so my details my be a bit mixed up, however, the grapefruit thing is spot on!
hope that this helps answer your question..
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