... been on Xyrem about two weeks. As of last Thursday ive had an almost constant headache. I started drinking Pedialyte thinking that rehydrating was a good idea, but then the pharmacist says that its the high salt content that may be contributing to the headaches. So pedialyte is not the way to go. She did say that most patients start to have fewer incidences of headache after about a month. I'm hoping hoping hoping. Anyone have any experience or knowledge about this? I'm hesitant to take NSAID's b/c I have digestive issues. Xyrem is one of my last hopes. I have fibromyalgia and have tried almost every other sleep med on the market
Headaches with Xyrem. Does anyone know what causes the headache side effect with Xyrem? I've only?
- Asked
- 2 Jun 2015 by humblegina
- Updated
- 30 July 2015
- Topics
- xyrem, headache, side effect
Responses (1)
It is definitely the extra sodium causing the headaches. I would recommend lowering your sodium intake through food and drinking plenty of water every day

Further Information
- Xyrem Information for Consumers
- Xyrem Information for Healthcare Professionals (includes dosage details)
- Side Effects of Xyrem (detailed)
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