Per my new endocrinologist, I am now taking my pill at bedtime instead of morning. This was suggested so I can start takiny my calcium first thing in the morning w/o worry that the levothyroxine will not be absorbed. Has anyone noticed a difference in the way they feel doing this too? Altho' my numbers are excellent (my TSH is a #1 now!), I still feel lethargic, especially in the earlier part of the day upon waking up. I never felt this way before. I get up later and feel less rested. Before this, I woke up with less sleep and felt more energy. Thanks.